Publications - Publications https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Bcontroller%5D=Publications&cHash=b9ee6d471ac671e9b20804c309d72c1b en-us PURE Extension typo3support@science.au.dk (Web Department) 30 <![CDATA[Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the COVID-19 pandemic]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=14c9909d-bdba-4219-8c86-62c79d1dd447&tx_pure_pure5%5BshowType%5D=pub&cHash=11314635b9505384b1947b1b8ce1df1c Schumacher, A. E., Kyu, H. H., Aali, A., et al. Background: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 countries and territories and 811 additional subnational locations from 1950 to 2021, with a particular emphasis on changes in mortality and life expectancy that occurred during the 2020–21 COVID-19 pandemic period. Methods: 22 223 data sources from vital registration, sample registration, surveys, censuses, and other sources were used to estimate mortality, with a subset of these sources used exclusively to estimate excess mortality due to the COVID-19 pandemic. 2026 data sources were used for population estimation. Additional sources were used to estimate migration; the effects of the HIV epidemic; and demographic discontinuities due to conflicts, famines, natural disasters, and pandemics, which are used as inputs for estimating mortality and population. Spatiotemporal Gaussian process regression (ST-GPR) was used to generate under-5 mortality rates, which synthesised 30 763 location-years of vital registration and sample registration data, 1365 surveys and censuses, and 80 other sources. ST-GPR was also used to estimate adult mortality (between ages 15 and 59 years) based on information from 31 642 location-years of vital registration and sample registration data, 355 surveys and censuses, and 24 other sources. Estimates of child and adult mortality rates were then used to generate life tables with a relational model life table system. For countries with large HIV epidemics, life tables were adjusted using independent estimates of HIV-specific mortality generated via an epidemiological analysis of HIV prevalence surveys, antenatal clinic serosurveillance, and other data sources. Excess mortality due to the COVID-19 pandemic in 2020 and 2021 was determined by subtracting observed all-cause mortality (adjusted for late registration and mortality anomalies) from the mortality expected in the absence of the pandemic. Expected mortality was calculated based on historical trends using an ensemble of models. In location-years where all-cause mortality data were unavailable, we estimated excess mortality rates using a regression model with covariates pertaining to the pandemic. Population size was computed using a Bayesian hierarchical cohort component model. Life expectancy was calculated using age-specific mortality rates and standard demographic methods. Uncertainty intervals (UIs) were calculated for every metric using the 25th and 975th ordered values from a 1000-draw posterior distribution. Findings: Global all-cause mortality followed two distinct patterns over the study period: age-standardised mortality rates declined between 1950 and 2019 (a 62·8% [95% UI 60·5–65·1] decline), and increased during the COVID-19 pandemic period (2020–21; 5·1% [0·9–9·6] increase). In contrast with the overall reverse in mortality trends during the pandemic period, child mortality continued to decline, with 4·66 million (3·98–5·50) global deaths in children younger than 5 years in 2021 compared with 5·21 million (4·50–6·01) in 2019. An estimated 131 million (126–137) people died globally from all causes in 2020 and 2021 combined, of which 15·9 million (14·7–17·2) were due to the COVID-19 pandemic (measured by excess mortality, which includes deaths directly due to SARS-CoV-2 infection and those indirectly due to other social, economic, or behavioural changes associated with the pandemic). Excess mortality rates exceeded 150 deaths per 100 000 population during at least one year of the pandemic in 80 countries and territories, whereas 20 nations had a negative excess mortality rate in 2020 or 2021, indicating that all-cause mortality in these countries was lower during the pandemic than expected based on historical trends. Between 1950 and 2021, global life expectancy at birth increased by 22·7 years (20·8–24·8), from 49·0 years (46·7–51·3) to 71·7 years (70·9–72·5). Global life expectancy at birth declined by 1·6 years (1·0–2·2) between 2019 and 2021, reversing historical trends. An increase in life expectancy was only observed in 32 (15·7%) of 204 countries and territories between 2019 and 2021. The global population reached 7·89 billion (7·67–8·13) people in 2021, by which time 56 of 204 countries and territories had peaked and subsequently populations have declined. The largest proportion of population growth between 2020 and 2021 was in sub-Saharan Africa (39·5% [28·4–52·7]) and south Asia (26·3% [9·0–44·7]). From 2000 to 2021, the ratio of the population aged 65 years and older to the population aged younger than 15 years increased in 188 (92·2%) of 204 nations. Interpretation: Global adult mortality rates markedly increased during the COVID-19 pandemic in 2020 and 2021, reversing past decreasing trends, while child mortality rates continued to decline, albeit more slowly than in earlier years. Although COVID-19 had a substantial impact on many demographic indicators during the first 2 years of the pandemic, overall global health progress over the 72 years evaluated has been profound, with considerable improvements in mortality and life expectancy. Additionally, we observed a deceleration of global population growth since 2017, despite steady or increasing growth in lower-income countries, combined with a continued global shift of population age structures towards older ages. These demographic changes will likely present future challenges to health systems, economies, and societies. The comprehensive demographic estimates reported here will enable researchers, policy makers, health practitioners, and other key stakeholders to better understand and address the profound changes that have occurred in the global health landscape following the first 2 years of the COVID-19 pandemic, and longer-term trends beyond the pandemic. Funding: Bill & Melinda Gates Foundation.

]]>
Research Sat, 18 May 2024 22:52:25 +0200 14c9909d-bdba-4219-8c86-62c79d1dd447
<![CDATA[Amino acid requirements for BSFL]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=613aa863-119d-46d7-b79d-f4c9d91ee12e&tx_pure_pure5%5BshowType%5D=pub&cHash=17334f39000263842d01b465092fcf7c Schøn, M. L., Berggreen, I. E., Jensen, K., Nørgaard, J. V. Research Wed, 06 Dec 2023 22:52:25 +0100 613aa863-119d-46d7-b79d-f4c9d91ee12e <![CDATA[Dairy cows’ motivation to nurse their calves]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=fda15028-06f9-4a00-9098-89f9c5d094b6&tx_pure_pure5%5BshowType%5D=pub&cHash=d8aff9a0ce371caf06fba592a173d664 Jensen, E. H., Bateson, M., Neave, H. W., Rault, J. L., Jensen, M. B. When weaning offspring, female mammals limit nursing opportunities. This study aimed to investigate whether imposing a gradual reduction in daily contact time, by separating cows from their calves as an attempt to stimulate weaning, reduced dairy cows’ motivation to nurse their calves. For seven weeks, 84 Holstein–Friesian cow-calf pairs were housed with either full-time (23 h contact/d), part-time (10 h contact/d), or no contact. In the following two weeks, half of full- and part-time pairs were subjected to reduced contact (50% of initial contact in week 8, 25% of initial contact in week 9), while the other half continued with unchanged contact. In weeks 8 and 9, cows’ motivation to obtain full contact to and opportunity to nurse their calves was measured using weighted push gates using a novel maximum price paid method providing an alternative choice to the cows to reduce frustration. Cows with reduced calf contact were more motivated than cows with unchanged contact; however, cows used the alternative choice less than expected. The results show that cows’ motivation for full calf contact and opportunity to nurse increases when daily calf contact is reduced, illustrating that dairy cows are motivated to continue nursing their 9- to 10-week-old calves.

]]>
Research Sun, 01 Dec 2024 22:52:25 +0100 fda15028-06f9-4a00-9098-89f9c5d094b6
<![CDATA[Biomarkers for ideal protein]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=7abfecba-961d-4d67-b378-24e26bcda920&tx_pure_pure5%5BshowType%5D=pub&cHash=81cd6c7224871d170b2c17dfb845adb0 Marín-García, P. J., Llobat, L., Cambra-López, M., et al. With the main aim of identifying biomarkers that contribute to defining the concept of ideal protein in growing rabbits under the most diverse conditions possible this work describes two different experiments. Experiment 1: 24 growing rabbits are included at 56 days of age. The rabbits are fed ad libitum one of the two experimental diets only differing in lysine levels. Experiment 2: 53 growing rabbits are included at 46 days of age, under a fasting and eating one of the five experimental diets, with identical chemical composition except for the three typically limiting amino acids (being fed commercial diets ad libitum in both experiments). Blood samples are taken for targeted and untargeted metabolomics analysis. Here we show that the metabolic phenotype undergoes alterations when animals experience a rapid dietary shift in the amino acid levels. While some of the differential metabolites can be attributed directly to changes in specific amino acids, creatinine, urea, hydroxypropionic acid and hydroxyoctadecadienoic acid are suggested as a biomarker of amino acid imbalances in growing rabbits’ diets, since its changes are not attributable to a single amino acid. The fluctuations in their levels suggest intricate amino acid interactions. Consequently, we propose these metabolites as promising biomarkers for further research into the concept of the ideal protein using rabbit as a model.

]]>
Research Sun, 01 Dec 2024 22:52:25 +0100 7abfecba-961d-4d67-b378-24e26bcda920
<![CDATA[Delineating Mastitis Cases in Dairy Cows]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=68350ed1-e61b-4a82-be7c-7b153dad1561&tx_pure_pure5%5BshowType%5D=pub&cHash=ab1cdb6d9daffcd2af8379d3c1eacd35 Khan, M. F., Thorup, V. M., Luo, Z. Mastitis, an intramammary bacterial infection, is not only known to adversely affect the health of a dairy cow but also to cause significant economic loss to the dairy industry. The severity and spread of mastitis can be restrained by identifying the early signs of infection in the cows through an intelligent decision support system. Early intervention and control of infection largely depend on the availability of on-site high throughput machinery, which can analyze milk samples regularly. However, due to limited resources, marginal and small farms usually cannot afford such high-end machinery, hence, the financial loss in such farms due to mastitis may become significant. To overcome such limitations, this article proposes a low-complexity yet affordable automated system for accurate prediction of early signs of clinical mastitis infection in dairy cows. In this work, behavioral data collected through Internet of Things (IoT)-enabled wearable sensors for cows is utilized to develop a support vector machine (SVM) model for the daily prediction of mastitis cases in a dairy farm. The dataset from the research herd utilizes the information of 415 cows collected in the span of 4.75 years in which 75 cows had mastitis. In addition to relevant behavioral features, other statistically significant features, such as daily milk yield, lactation period, and age are also utilized as features. Our study indicates that the SVM model comprising a subset of behavioral and nonbehavioral features can deliver a mastitis prediction accuracy of 89.2&#x0025;.

]]>
Research Mon, 01 Jan 2024 22:52:25 +0100 68350ed1-e61b-4a82-be7c-7b153dad1561
<![CDATA[Forekomst af brom og bromforbindelser i tang til kvægfoder og den relaterede risiko for dyresundheden samt risiko for overførsel til fødevarer af animalsk oprindelse]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=575313ae-213d-4fe1-b3f2-f9e12046e16e&tx_pure_pure5%5BshowType%5D=pub&cHash=3c46d92a3a0f1c70d83a977ee9fc6f68 Nørskov, N. Commissioned Mon, 17 Jun 2024 22:52:25 +0200 575313ae-213d-4fe1-b3f2-f9e12046e16e <![CDATA[Delineation of chicken immune markers in the era of omics and multicolor flow cytometry]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=522cfa91-dcb6-44bc-b755-ba06212c9684&tx_pure_pure5%5BshowType%5D=pub&cHash=38108c5309bd657e05d840a10b31f4b0 Härtle, S., Sutton, K., Vervelde, L., Dalgaard, T. S. Multiparameter flow cytometry is a routine method in immunological studies incorporated in biomedical, veterinary, agricultural, and wildlife research and routinely used in veterinary clinical laboratories. Its use in the diagnostics of poultry diseases is still limited, but due to the continuous expansion of reagents and cost reductions, this may change in the near future. Although the structure and function of the avian immune system show commonalities with mammals, at the molecular level, there is often low homology across species. The cross-reactivity of mammalian immunological reagents is therefore low, but nevertheless, the list of reagents to study chicken immune cells is increasing. Recent improvement in multicolor antibody panels for chicken cells has resulted in more detailed analysis by flow cytometry and has allowed the discovery of novel leukocyte cell subpopulations. In this article, we present an overview of the reagents and guidance needed to perform multicolor flow cytometry using chicken samples and common pitfalls to avoid.

]]>
Research Wed, 01 May 2024 22:52:25 +0200 522cfa91-dcb6-44bc-b755-ba06212c9684
<![CDATA[Estimering af videns- og finansieringsbehov for opnåelse af klimamål i 2030]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=10147e05-2ea2-4f86-850f-6b268c671770&tx_pure_pure5%5BshowType%5D=pub&cHash=f376e0955c7a8c7f19e72276aac6d27d Olesen, J. E., Lund, P., Feilberg, A., et al. Commissioned Mon, 27 May 2024 22:52:25 +0200 10147e05-2ea2-4f86-850f-6b268c671770 <![CDATA[Animal-based methods for the assessment of broiler chicken welfare in organic and conventional production systems]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=6d3dadf3-0fad-4ed3-92c5-3d60b2de6902&tx_pure_pure5%5BshowType%5D=pub&cHash=933c2a248d995185c6ba2d920feeee01 Rasmussen, S. N., Wurtz, K. E., Erasmus, M., Riber, A. B. Animal welfare is one of the pillars in organic broiler production, evident in practices such as utilizing slower-growing hybrids and maintaining lower stocking densities for the birds. However, despite these efforts, skepticism and uncertainty remain regarding the extent to which animal welfare objectives are achieved in organic farming. The primary aim of this study was to compare animal-based measures assessing positive and negative welfare between organic and conventional broiler chickens in Denmark. The selected positive welfare indicators included Qualitative Behavior Assessment (QBA) and observations of play behavior in an open-space test. An additional aim of this study was to examine the reliability of the method by having all QBA observations done by two observers. Negative welfare indicators included walking ability assessed using the 6-point Bristol gait score method and fearfulness assessed using a novel object test. Welfare assessments were conducted on-farm before slaughter at 31–33 days of age for conventional birds and at 49–55 days of age for organic birds. The results from the QBA indicated differences between organic and conventional production systems (P = 0.001). Specifically, organic broilers exhibited higher levels of active, energetic, positively occupied, happy, and agitated behaviors. Notably, the outcome of the QBA was influenced by the observer (P = 0.001); on average, one observer tended to assign higher scores specifically for depressed and distressed behaviors, while the other observer allocated higher scores to the remaining behavioral terms. Moreover, organic broilers tended to show better walking abilities than conventional broilers (P = 0.064). Fear responses were similar across both production systems. Finally, organic broilers demonstrated a lower frequency of play behavior in open spaces compared to conventional broilers (P = 0.001). Conventional birds may have expressed more play behavior due to the greater contrast between the sudden availability of open space and their typical stocking density, resulting in increased compensatory play. This presents a challenge since a higher frequency of play is often considered an indicator of positive welfare, but we speculate whether in this study, it might suggest a restriction of spontaneous play due to space limitations caused by the high stocking density in the conventional production system. As a result, when additional space becomes available, it could lead to a rebound effect. Future research should explore how stocking density influences play behavior in broiler chickens, including measures of both spontaneous play and stimulated play during controlled test situations.

]]>
Research Mon, 01 Jul 2024 22:52:25 +0200 6d3dadf3-0fad-4ed3-92c5-3d60b2de6902
<![CDATA[Implementation of the Use of the Enteric Methane Mitigating Feed Additive Bovaer® in the National Danish Emission Inventories for Dairy Cows]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=b2d128e8-33f1-469e-8465-e2efc213eed0&tx_pure_pure5%5BshowType%5D=pub&cHash=3fb9b67d401913c83818c43a667aa549 Lund, P., Maigaard, M., Kjeldsen, M. H., et al. Commissioned Mon, 10 Jun 2024 22:52:25 +0200 b2d128e8-33f1-469e-8465-e2efc213eed0 <![CDATA[Vurdering af afkølingsmuligheder ved vand fremfor skygge for udegående kreaturer]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=f50c63eb-1767-452a-854d-1423ff8e18dc&tx_pure_pure5%5BshowType%5D=pub&cHash=dafb1a6ade8af4ccbf1c5a1b773f1246 Malmkvist, J., Jensen, M. B. Commissioned Fri, 31 May 2024 22:52:25 +0200 f50c63eb-1767-452a-854d-1423ff8e18dc <![CDATA[Feed intake in housed dairy cows]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=a4684126-c7aa-4791-ae59-6b8db94ba4da&tx_pure_pure5%5BshowType%5D=pub&cHash=7a27e5ca0330f446dedea34fb2c5ffb7 Giagnoni, G., Lassen, J., Lund, P., Foldager, L., Johansen, M., Weisbjerg, M. R. Measuring feed intake accurately is crucial to determine feed efficiency and for genetic selection. A system using three-dimensional (3D) cameras and deep learning algorithms can measure the volume of feed intake in dairy cows, but for now, the system has not been validated for feed intake expressed as weight of feed. The aim of this study was to validate the weight of feed intake predicted from the 3D cameras with the actual measured weight. It was hypothesised that diet−specific coefficients are necessary for predicting changes in weight, that the relationship between weight and volume is curvilinear throughout the day, and that manually pushing the feed affects this relationship. Twenty-four lactating Danish Holstein cows were used in a cross-over design with four dietary treatments, 2 × 2 factorial arranged with either grass-clover silage or maize silage as silage factor, and barley or dried beet pulp as concentrate factor. Cows were adapted to the diets for 11 d, and for 3 d to tie-stall housing before camera measurements. Six cameras were used for recording, each mounted over an individual feeding platform equipped with a weight scale. When building the predictive models, four cameras were used for training, and the remaining two for testing the prediction of the models. The most accurate predictions were found for the average feed intake over a period when using the starting density of the feed pile, which resulted in the lowest errors, 6% when expressed as RMSE and 5% expressed as mean absolute error. A model including curvilinear effects of feed volume and the impact of manual feed pushing was used on a dataset including daily time points. When cross-validating, the inclusion of a curvilinear effect and a feed push effect did not improve the accuracy of the model for neither the feed pile nor the feed removed by the cow between consecutive time points. In conclusion, measuring daily feed intake from this 3D camera system in the present experimental setup could be accomplished with an acceptable error (below 8%), but the system should be improved for individual meal intake measurements if these measures were to be implemented.

]]>
Research Sat, 01 Jun 2024 22:52:25 +0200 a4684126-c7aa-4791-ae59-6b8db94ba4da
<![CDATA[FdeC expression regulates motility and adhesion of the avian pathogenic Escherichia coli strain IMT5155]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=54d6cb73-d151-4e4c-98c0-f2fed1f09d83&tx_pure_pure5%5BshowType%5D=pub&cHash=1af0cee9a2ffa6c8b99cdb96bc81dc45 Aleksandrowicz, A., Kjærup, R. B., Grzymajło, K., et al. Adaptation of avian pathogenic E. coli (APEC) to changing host environments including virulence factors expression is vital for disease progression. FdeC is an autotransporter adhesin that plays a role in uropathogenic Escherichia coli (UPEC) adhesion to epithelial cells. Expression of fdeC is known to be regulated by environmental conditions in UPEC and Shiga toxin-producing E. coli (STEC). The observation in a previous study that an APEC strain IMT5155 in which the fdeC gene was disrupted by a transposon insertion resulted in elevated adhesion to chicken intestinal cells prompted us to further explore the role of fdeC in infection. We found that the fdeC gene prevalence and FdeC variant prevalence differed between APEC and nonpathogenic E. coli genomes. Expression of the fdeC gene was induced at host body temperature, an infection relevant condition. Disruption of fdeC resulted in greater adhesion to CHIC-8E11 cells and increased motility at 42 °C compared to wild type (WT) and higher expression of multiple transporter proteins that increased inorganic ion export. Increased motility may be related to increased inorganic ion export since this resulted in downregulation of YbjN, a protein known to supress motility. Inactivation of fdeC in APEC strain IMT5155 resulted in a weaker immune response in chickens compared to WT in experimental infections. Our findings suggest that FdeC is upregulated in the host and contributes to interactions with the host by down-modulating motility during colonization. A thorough understanding of the regulation and function of FdeC could provide novel insights into E. coli pathogenesis.

]]>
Research Wed, 01 May 2024 22:52:25 +0200 54d6cb73-d151-4e4c-98c0-f2fed1f09d83
<![CDATA[Effect of grinding or rolling fava beans on feed intake and milk production in Holstein cows]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=dad4c3f9-1cf7-429f-b8c6-7aeb369b642e&tx_pure_pure5%5BshowType%5D=pub&cHash=44d7e196b01834b2be73292ced651b74 Rozada, T. d. E., Johansen, M., Weisbjerg, M. R., Larsen, M. The objective of the present study was to evaluate the performance of primi- and multiparous dairy cows fed diets with ground or rolled fava beans (FB). A total of 96 Danish Holstein cows (48 primi- and 48 multiparous) were used in a randomized block design lasting 4 weeks. Within parity group, cows were blocked according to their milk yield in 6 blocks with 8 cows each and two cows from each block were distributed in pens where they were assigned randomly one of the two experimental diets. The diets were based on a total mix ration (TMR) composed of 52.6 % forage and 47.4 % concentrate (DM basis), differing only in the particle size of FB (geometric mean diameters of 1.02 and 3.52 mm for ground and rolled FB, respectively). Feed intake, milk production, and milk composition were determined during the last 8 days of the experimental period; none of these differed between treatments except for a higher (P = 0.01) milk N efficiency (% of N intake) and milk urea content with ground FB compared with rolled FB. Additionally, feces and ruminal fluid were collected from a group of 24 multiparous cows to determine fecal starch content and ruminal volatile fatty acids (VFAs). The fecal starch concentration was greater with rolled FB showing a reduced starch digestion, whereas ruminal VFA proportions generally did not differ between treatments. In conclusion, the lactation performance of dairy cows appeared not to be affected by grinding or rolling of FB with a 20 % FB inclusion in the DM diet, even though total tract starch digestion was reduced with greater FB particle size.

]]>
Research Mon, 01 Jul 2024 22:52:25 +0200 dad4c3f9-1cf7-429f-b8c6-7aeb369b642e
<![CDATA[Effect of different feeding strategies and dietary fiber levels on energy and protein retention in gestating sows]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=a183245f-0251-453d-84c0-a041963e8e3f&tx_pure_pure5%5BshowType%5D=pub&cHash=9fc749a789a5012c390cabcbcc144462 Wisbech, S. J., Nielsen, T. S., Bach Knudsen, K. E., Theil, P. K., Bruun, T. S. The aim of the study was to investigate whether increased inclusion of sugar beet pulp (SBP) alters retention of fat, protein, and energy when backfat (BF) is restored in early- and mid-gestation. In total, 46 sows were fed one of four dietary treatments with increasing inclusion of SBP providing dietary fiber (DF) levels of 119, 152, 185, and 217 g/kg; sows were assigned to one of three feeding strategies (FS; high, medium, and low) depending on BF thickness at mating and again at day 30 for the following month. On days 0, 30, 60, and 108, body weight (BW) and BF thickness were measured and body pools of protein and fat were estimated using the deuterium oxide technique. On days 30 and 60, urine, feces, and blood samples were collected to quantify metabolites, energy, and nitrogen (N) balances. On days 15 and 45, heart rate was recorded to estimate heat energy. At farrowing, total born and weight of the litter were recorded. In early gestation, BW gain (P < 0.01) and body protein retention increased (P < 0.05) with increasing fiber inclusion, while body fat retention increased numerically by 59%. The increase in BF was greatest for sows fed the high FS, intermediate when fed the medium strategy, and negligible for sows fed the lowest FS (P < 0.001). Nitrogen intake, N loss in feces, and N balance increased linearly, whereas N loss in urine tended to decrease with increasing inclusion of fibers in early gestation. Concomitantly, fecal energy output and energy lost as methane increased linearly (P < 0.001), while energy output in urine declined linearly. Total metabolizable energy (ME) intake therefore increased from 36.5 MJ ME/d in the low fiber group to 38.5 MJ ME/d in the high fiber group (P < 0.01). Changing the ME towards more ketogenic energy was expected to favor fat retention rather than protein retention. However, due to increased intake of ME and increased N efficiency with increasing fiber inclusion, the sows gained more weight and protein with increas¬ing fiber inclusion. In conclusion, increased feed intake improved both fat and protein retention, whereas increased DF intake increased protein retention.

]]>
Research Mon, 01 Apr 2024 22:52:25 +0200 a183245f-0251-453d-84c0-a041963e8e3f
<![CDATA[<i>Ulva </i>species: A critical review on the green seaweed as a source of food protein]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=91c7b008-2020-4f4b-878b-857ca16ac4b3&tx_pure_pure5%5BshowType%5D=pub&cHash=6a3a37fe7301dd36e43820636485f09c Juul, L., Nissen, S. H., Bruhn, A., et al. Background: Green macroalgae of the Ulva genus have gained interest as a source of protein, due to the high production potential and high proportion of essential amino acids. This review gives an overview of Ulva protein, including extraction and evaluation of protein quality in terms of nutritional value, functionality, and sensory properties with preliminary suggestions to reach the market. Scope and approach: Available literature on protein extraction from Ulva was reviewed along with studies investigating the nutritional quality of Ulva protein and functional properties including aroma and flavor characteristics. Opportunities, challenges, and knowledge gaps are presented. Key findings and conclusion: A range of studies are investigating protein extraction, but only a few studies have dealt with protein digestibility, and food protein products. The digestibility of protein in crude Ulva biomass is low compared to conventional protein sources but increase with protein extraction. Sensory and functionality studies on Ulva protein are yet absent, but the whole biomass has been investigated, indicating the potential. The lack of consisting studies calls for more investigations related to food quality of Ulva protein. Upscaling and biorefinery models need to be explored to unfold the true potential of Ulva as a source of food protein.

]]>
Research Mon, 01 Jul 2024 22:52:25 +0200 91c7b008-2020-4f4b-878b-857ca16ac4b3
<![CDATA[Distribution of oxygen in marine sediments measured with microelectrodes]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=36cfc3ee-42d4-4625-9465-158fa925284d&tx_pure_pure5%5BshowType%5D=pub&cHash=f74ccca6bd022340c49df0a139bfe701 Revsbech, N. P., Sorensen, J., Blackburn, T. H., Lomholt, J. P. This article is in Free Access Publication and may be downloaded using the “Download Full Text PDF” link at right.

]]>
Research Thu, 01 May 1980 22:52:25 +0200 36cfc3ee-42d4-4625-9465-158fa925284d
<![CDATA[Ecological Civilisation and Amphibian Sustainability through Reproduction Biotechnologies, Biobanking, and Conservation Breeding Programs (RBCs)]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=5b7c404b-ab04-4e68-bbbd-2391c34091f5&tx_pure_pure5%5BshowType%5D=pub&cHash=bc6b5bdaf85df6b9328b792950ae7042 Browne, R. K., Luo, Q., Wang, P., et al. Intergenerational justice entitles the maximum retention of Earth’s biodiversity. The 2022 United Nations COP 15, “Ecological Civilisation: Building a Shared Future for All Life on Earth”, is committed to protecting 30% of Earth’s terrestrial environments and, through COP 28, to mitigate the effects of the climate catastrophe on the biosphere. We focused this review on three core themes: the need and potential of reproduction biotechnologies, biobanks, and conservation breeding programs (RBCs) to satisfy sustainability goals; the technical state and current application of RBCs; and how to achieve the future potentials of RBCs in a rapidly evolving environmental and cultural landscape. RBCs include the hormonal stimulation of reproduction, the collection and storage of sperm and oocytes, and artificial fertilisation. Emerging technologies promise the perpetuation of species solely from biobanked biomaterials stored for perpetuity. Despite significant global declines and extinctions of amphibians, and predictions of a disastrous future for most biodiversity, practical support for amphibian RBCs remains limited mainly to a few limited projects in wealthy Western countries. We discuss the potential of amphibian RBCs to perpetuate amphibian diversity and prevent extinctions within multipolar geopolitical, cultural, and economic frameworks. We argue that a democratic, globally inclusive organisation is needed to focus RBCs on regions with the highest amphibian diversity. Prioritisation should include regional and international collaborations, community engagement, and support for RBC facilities ranging from zoos and other institutions to those of private carers. We tabulate a standard terminology for field programs associated with RBCs for publication and media consistency.

]]>
Research Wed, 01 May 2024 22:52:25 +0200 5b7c404b-ab04-4e68-bbbd-2391c34091f5
<![CDATA[Svar på Spørgsmål til AU-ANIVET i forbindelse med KU-IFRO’ vurderinger af omkostningerne til metanreducerende fodringstiltag]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=4238052a-3f7d-473c-91ca-8a7e156f908b&tx_pure_pure5%5BshowType%5D=pub&cHash=ea6f67d9815531ad86038b3fd52803b7 Weisbjerg, M. R., Børsting, C. F., Lund, P. Commissioned Fri, 31 May 2024 22:52:25 +0200 4238052a-3f7d-473c-91ca-8a7e156f908b <![CDATA[Hemizygous minipigs produced by random gene insertion and handmade cloning express the Alzheimer's disease-causing dominant mutation APPsw]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=a0c07228-3cf7-4578-b1ea-0336eb894665&tx_pure_pure5%5BshowType%5D=pub&cHash=365e4b04ae1f0dcb8e96216f2ddb55ee Kragh, P. M., Nielsen, A. L., Li, J., et al. In an effort to develop a porcine model of Alzheimer's disease we used handmade cloning to produce seven transgenic Göttingen minipigs. The donor fibroblasts had been stably transfected with a plasmid cassette containing, as transgene, the cDNA of the neuronal variant of the human amyloid precursor protein gene with the Swedish mutation preceded by beta-globin sequences to induce splicing and a human PDGF beta promoter fragment to drive transcription. Transgene insertion had occurred only at the GLIS3 locus where a single complete copy of the transgene was identified in intronic sequences in opposite direction. Similar and robust levels of the transgene transcript were detected in skin biopsies from all piglets and the sequence of full-length transcript was verified. Consistent with PDGF beta promoter function, high levels of transgene expression, including high level of the corresponding protein, was observed in brain tissue and not in heart or liver tissues. A rough estimate predicts that accumulation of the A beta peptide in the brain may develop at the age of 1-2 years.

]]>
Research Sat, 01 Aug 2009 22:52:25 +0200 a0c07228-3cf7-4578-b1ea-0336eb894665
<![CDATA[Salmonella overlever længe i sand]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=126f5adc-61c6-4e03-8de7-e86fc9114050&tx_pure_pure5%5BshowType%5D=pub&cHash=edebe69fcae76685fe1c603a7c8b9174 Thomsen, P. T. Communication Wed, 01 May 2024 22:52:25 +0200 126f5adc-61c6-4e03-8de7-e86fc9114050 <![CDATA[Key determinants of adaptive strategies of goats to a 2-day nutritional challenge during early lactation]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=865becf5-aee6-443d-bfa4-b94a8b0bc365&tx_pure_pure5%5BshowType%5D=pub&cHash=ff9eabd2bc74fbf1f73acbba3ae6feaf Gindri, M., Friggens, N. C., Dhumez, O., et al. Little is known about the key determinants of the physiological adaptations to environmental challenges and how these determinants interact. We evaluated how the response/recovery profiles to a short-term nutritional challenge during early lactation are affected by early-life nutritional strategies in dairy goats divergently selected for functional longevity. We used 72 females, split into two cohorts, daughters of Alpine bucks divergently selected for functional longevity. The females from the two lines were fed with two divergent diets, normal vs low-energy, from weaning until the middle of first gestation, and then fed with the same standard diet. Individual BW, body condition score, morphology, and plasma samples were collected from birth to first kidding. The adaptative physiological strategy to a nutritional challenge was assessed via a 2-day feed restriction challenge, during early lactation, which consisted of a five-day control period on a standard lactation diet followed by a 2-day challenge with straw-only feeding and then a 10-day recovery period on a standard lactation diet. During the challenge, DM intake, BW, milk yield (MY), and plasma and milk metabolite composition were recorded daily. Linear mixed-effects models were used to analyze all traits, considering the individual nested in the cohort as a random effect and the 2 × 2 treatments (i.e., line and rearing diet) and litter size as fixed effects. Linear mixed-effects models using a piecewise arrangement were used to analyze the response/recovery profiles to nutritional challenge. Random parameters estimated for each individual, using the mixed-effects models without the fixed effects of rearing diet and genetic line, were used in a stepwise model selection based on R2 to identify key determinants of an individual's physiological adaptations to environmental challenges. Differences in stature and body reserves created by the two rearing diets diminished during late gestation and the 5-day control period. Genetic line did not affect body reserves during the rearing phase. Rearing diet and genetic line slightly affected the recovery profiles of evaluated traits and had no effects on prechallenge and response to challenge profiles. The prekidding energy status measures and MY before challenge were selected as strong predictors of variability in response-recovery profiles of milk metabolites that have strong links with body energy dynamics (i.e., isoCitrate, ß-hydroxybutyrate, choline, cholesterol, and triacylglycerols; R2 = 35%). Our results suggested that prekidding energy status and MY are key determinants of adult resilience and that rearing diet and genetic line may affect adult resilience insofar as they affect the animals’ energy status.

]]>
Research Sat, 01 Jun 2024 22:52:25 +0200 865becf5-aee6-443d-bfa4-b94a8b0bc365
<![CDATA[Dark brooder pullets are less active than Non-brooder pullets, but show similar level of synchronisation at the resource areas]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=6893123a-7a4f-4cba-a2cd-87b9a2422eeb&tx_pure_pure5%5BshowType%5D=pub&cHash=25e1cfad0e7853834fba18682ec423df Martin-Cicera, A., Lyrakis, M., Riber, A. B., et al. Maternal care in commercial chickens can partially be replaced with dark brooders that offer heat and a dark area to rest and possibly avoid negative social interactions. Previous research has established the positive effects of dark brooders on reducing disturbance during resting in young pullets and injurious pecking in pullets and laying hens, which could reduce overall activity levels. The objective of this study was to employ precision livestock farming techniques to compare the overall activity levels and behavioural synchrony at resources in pullets reared with dark brooders until 41 days of age and those reared with whole house heating. Four brooder treatments, varying in size (Small/Large) and deployment method (Raised/Fixed), which could have implications for commercial use, were employed. Activity of the whole pen floor area and behavioural synchrony in drinker and feeder areas were automatically assessed over a 12-hour photoperiod at 10 and 60 days of age. Pixel change detection gauged overall activity across the pen, while an object detection model evaluated pullet behavioural synchrony. The analysis revealed increased activity levels in non-Brooder pullets compared to those in most Brooder treatments at both 10 and 60 days of age. However, no significant differences in behavioural synchrony were observed between Brooder and non-Brooder pullets. The underlying mechanism of dark brooder's effects on the activity levels and behaviour synchrony remains unclear, but the observed reduction in activity levels in brooded pullets likely corresponds to increased resting behaviour and reduced injurious pecking. Furthermore, it is noteworthy that only a small percentage of pullets (up to 57.14%) were observed to use the resources simultaneously. This underscores the importance of conducting additional research to delve into the effects of resource allocation on both behavioural synchrony and activity levels in pullets. We observed minimal differences in the behaviour of pullets raised under different brooder types, suggesting that the simplest (Small-Fixed) brooders may be suitable for commercial use.

]]>
Research Sat, 01 Jun 2024 22:52:25 +0200 6893123a-7a4f-4cba-a2cd-87b9a2422eeb
<![CDATA[A scoping review of the use of bioacoustics to assess various components of farm animal welfare]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=4ad67cda-02af-4746-b5fd-92f5071a999a&tx_pure_pure5%5BshowType%5D=pub&cHash=22e85c20f47736fb5ca30835ec57f9ae Coutant, M. P., Villain, A. S. ., Briefer, E. F. Research Sat, 01 Jun 2024 22:52:25 +0200 4ad67cda-02af-4746-b5fd-92f5071a999a <![CDATA[Bioacoustic sensors to monitor farm animal welfare: why the ethology matters]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=a446ed7f-7a5a-48c7-8b5d-67c0d0ca6129&tx_pure_pure5%5BshowType%5D=pub&cHash=e5c804b96c1da1587de66da3cee6aae6 Coutant, M. P. Research Wed, 15 May 2024 22:52:25 +0200 a446ed7f-7a5a-48c7-8b5d-67c0d0ca6129 <![CDATA[The Relevance of Shame in Dog-Human Relationships]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=484af99f-804f-4a20-9e0f-cc536fd298a5&tx_pure_pure5%5BshowType%5D=pub&cHash=a5d086235573bbf480199bbe8700ddc1 Kollerup Oftedal, L., Harfeld, J. L. Research Mon, 01 Jun 2020 22:52:25 +0200 484af99f-804f-4a20-9e0f-cc536fd298a5 <![CDATA[A high fat to vitamin E ratio in the feed protects and improves uptake of the natural form of vitamin E in postweaning calves]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=51ad5c57-19ea-4880-b423-9ce2708c6254&tx_pure_pure5%5BshowType%5D=pub&cHash=42f1eb1b899a3d3e99e1b63ccc2556f6 Lashkari, S., Jensen, S. K., Foldager, L., Larsen, T., Vestergaard, M. . In postweaning calves, it is a challenge to maintain the plasma vitamin E level at or above the recommended level (3 µg/mL), which is linked to a good immune response. It has been unclear until now why the provision of solid feed with concentrations below 200 mg/kg feed of vitamin E is ineffective in maintaining the plasma vitamin E level of calves above the recommended plasma level postweaning. The present study was conducted to investigate if a high fat to vitamin E ratio in the concentrate could protect and improve the delivery of the natural form of vitamin E (RRR-α-tocopherol) to calves postweaning. Thirty calves were included in the experiment from 2 weeks preweaning until 2 weeks postweaning (Weeks −2, −1, 0 [weaning], 1, and 2 relative to weaning) and fed one of three concentrates in which lecithin mixture provided the fat supplement: control (77 mg/kg of vitamin E and 4.9% DM of crude fat; CONT), medium level of vitamin E supplemented (147 mg/kg of vitamin E and 7.7% DM of crude fat; MedVE) or high level of vitamin E supplemented (238 mg/kg of vitamin E and 12.4% DM of fat; HiVE). Thus, there was a comparable ratio of fat to vitamin E (520–630) in the three concentrates. During the 2 weeks postweaning, final body weight (92 ± 2 kg), average daily gain (917 ± 51 g/day) and concentrate intake (2.2 ± 0.09 kg/day; mean of treatment ± standard error) were unaffected by treatment and the interaction between treatment and week. There was an interaction between treatment and week for vitamin E intake pre- (p < 0.001) and postweaning (p < 0.001). There was an interaction between treatment and week (p < 0.001) for plasma vitamin E level postweaning, and it was 2.5, 3.1, and 3.8 µg/mL in CONT, MedVE, and HiVE, respectively, at Week 1 postweaning. In addition, plasma vitamin E levels at Week 2 postweaning were 2.6, 3.6 and 4.8 µg/mL in CONT, MidVE and HiVE respectively. The results show that 147 mg/kg of lecithin-protected vitamin E in the concentrate is needed to secure a plasma vitamin E level well above the recommended level. In addition, lecithin-protected vitamin E elevated the plasma level of triglycerides and nonesterified fatty acids.

]]>
Research Wed, 01 May 2024 22:52:25 +0200 51ad5c57-19ea-4880-b423-9ce2708c6254
<![CDATA[Two millennia of climate change, wildfires, and caribou hunting in west Greenland]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=101460ba-5e37-4183-867d-38b18c6b57c8&tx_pure_pure5%5BshowType%5D=pub&cHash=ae030f4e86acd99ef7336d946d233b4e Strunk, A., Krüger, S., Jensen, J. F., Olsen, J., Jessen, C. Changing climatic conditions is a perpetual circumstance for mankind. In this study, we investigate local environmental and climatic changes near Kangerlussuaq, west Greenland. Our reconstruction is based on a lake sediment core and methods include chemical proxies and a palynological analysis. The investigated site is located 15 km from the Aasivissuit Inuit summer hunting ground, which has been in use for caribou hunting for more than 2000 years. The presented climatic reconstruction covers the time from c. 560 CE to present time. We identify three distinct periods of climate regimes: From c. 560–1100 CE conditions were stable, warm and humid, and summer temperatures were 1.5–2°C warmer than today. 1100–1600 was a period of cooler and very arid conditions with more sea ice, corresponding to the Neoglacial cooling. In this period, we detect two wildfire events and subsequent temporary caribou abandonment of the area. From 1600 to present we find increasingly warmer conditions with more precipitation and less extensive sea ice cover, gradually approaching today’s climate regime in Kangerlussuaq. We review the existing literature regarding the Aasivissuit summer hunting ground, which was first used concurrently with the detected cooling. Despite climatic deterioration, the hunting ground was regularly in use throughout the Neoglacial and onwards, with peak hunting intensity in the early 1700s. The detected wildfires and reindeer abandonment are interpreted to be localized events at the coring site and did not affect the hunting ground. Our findings highlight the resilience of the Inuit hunters to climatic changes as well as the advantages and limitations of local environmental reconstructions.

]]>
Research Mon, 01 Jan 2024 22:52:25 +0100 101460ba-5e37-4183-867d-38b18c6b57c8
<![CDATA[Protecting the piglet gut microbiota against ETEC-mediated post-weaning diarrhoea using specific binding proteins]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=25bc36d4-b2ce-46e9-9d81-366350fad424&tx_pure_pure5%5BshowType%5D=pub&cHash=7906a2c3bd4488be5979b0e7cc0040a1 Jenkins, T. P., Ács, N., Arendrup, E. W., et al. Post-weaning diarrhoea (PWD) in piglets presents a widespread problem in industrial pig production and is often caused by enterotoxigenic E. coli (ETEC) strains. Current solutions, such as antibiotics and medicinal zinc oxide, are unsustainable and are increasingly being prohibited, resulting in a dire need for novel solutions. Thus, in this study, we propose and evaluate a protein-based feed additive, comprising two bivalent heavy chain variable domain (VHH) constructs (VHH-(GGGGS)3-VHH, BL1.2 and BL2.2) as an alternative solution to manage PWD. We demonstrate in vitro that these constructs bind to ETEC toxins and fimbriae, whilst they do no affect bacterial growth rate. Furthermore, in a pig study, we show that oral administration of these constructs after ETEC challenge reduced ETEC proliferation when compared to challenged control piglets (1-2 log10 units difference in gene copies and bacterial count/g faeces across day 2–7) and resulted in week 1 enrichment of three bacterial families (Prevotellaceae (estimate: 1.12 ± 0.25, q = 0.0054), Lactobacillaceae (estimate: 2.86 ± 0.52, q = 0.0012), and Ruminococcaceae (estimate: 0.66 ± 0.18, q = 0.049)) within the gut microbiota that appeared later in challenged control piglets, thus pointing to an earlier transition towards a more mature gut microbiota. These data suggest that such VHH constructs may find utility in industrial pig production as a feed additive for tackling ETEC and reducing the risk of PWD in piglet populations.

]]>
Research Wed, 01 May 2024 22:52:25 +0200 25bc36d4-b2ce-46e9-9d81-366350fad424
<![CDATA[Variations in salivary oxytocin and eye caruncle temperature indicate response to environmental enrichment material in fattening pigs]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=1a64a109-c51c-4c63-8fd5-e830af8a04ea&tx_pure_pure5%5BshowType%5D=pub&cHash=1046e77ee9e91129888dcc14fc5ff73e Amorim Franchi, G., R. Moscovice, L., Telkänranta, H., Pedersen, L. J. Research Sat, 01 Jun 2024 22:52:25 +0200 1a64a109-c51c-4c63-8fd5-e830af8a04ea <![CDATA[Variations in the persistence of 5′-end genomic and subgenomic SARS-CoV-2 RNAs in wastewater from aircraft, airports and wastewater treatment plants]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=c80fd1af-fd36-4e9a-a898-210ae348d2c7&tx_pure_pure5%5BshowType%5D=pub&cHash=63cd503ab0d373ec583d0b6f1fd74868 Tang, M. H. E., Bennedbaek, M., Gunalan, V., et al. Wastewater sequencing has become a powerful supplement to clinical testing in monitoring SARS-CoV-2 infections in the post-COVID-19 pandemic era. While its applications in measuring the viral burden and main circulating lineages in the community have proved their efficacy, the variations in sequencing quality and coverage across the different regions of the SARS-CoV-2 genome are not well understood. Furthermore, it is unclear how different sample origins, viral extraction and concentration methods and environmental factors impact the reads sequenced from wastewater. Using high-coverage, amplicon-based, paired-end read sequencing of viral RNA extracted from wastewater collected directly from aircraft, pooled from different aircraft and airport buildings or from regular wastewater plants, we assessed the genome coverage across the sample groups with a focus on the 5′-end region covering the leader sequence and investigated whether it was possible to detect subgenomic RNA from viral material recovered from wastewater. We identified distinct patterns in the persistence of the different genomic regions across the different types of wastewaters and the existence of chimeric reads mapping to non-amplified regions. Our findings suggest that preservation of the 5′-end of the genome and the ability to detect subgenomic RNA reads, though highly susceptible to environment and sample processing conditions, may be indicative of the quality and amount of the viral RNA present in wastewater.

]]>
Research Wed, 01 May 2024 22:52:25 +0200 c80fd1af-fd36-4e9a-a898-210ae348d2c7
<![CDATA[Optimal protein concentration in diets for sows during the transition period]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=1cf44d50-10f0-4e02-b4b0-fc428612d08e&tx_pure_pure5%5BshowType%5D=pub&cHash=97098e1b18852dbc36cef8f63496bec2 Johannsen, J. C., Sorensen, M. T., Theil, P. K., Bruun, T. S., Farmer, C., Feyera, T. The aim of the present study was to determine the optimal concentration of dietary protein required in transition diets for multiparous sows that enhance the farrowing process, colostrum production, and subsequent lactation performance. Forty-eight multiparous sows were allotted to one of six dietary treatments according to body weight (290 ± 3 kg) and parity (3.8 ± 0.2) from day 108 of gestation until 24 h after the onset of farrowing. The diets were isoenergetic and contained increasing concentrations of dietary protein (expressed as standardized ileal digestible [SID] Lys) and were supplied at a daily feed supply of 3.8 kg. On day 108 of gestation and days 2, 7, 14, 21, and 28 of lactation, body weight, and back fat thickness were recorded, and blood was sampled on day 108 of gestation, at the onset of farrowing, and days 3, 10, 17, and 24 of lactation from the sows for analysis of plasma metabolites. On day 115 of gestation, urine, and feces were collected for nitrogen (N) balance. The number of liveborn and stillborn piglets and time of birth were recorded and blood from every fourth piglet was sampled at birth for blood gas analysis. Piglets were weighed individually from birth until weaning, to estimate the colostrum and milk yield of the sows. Colostrum and milk samples were collected, and their compositions were determined. On days 3 and 28 of lactation, sows were injected with deuterium oxide to estimate body composition. The N utilization was maximized when the concentration of SID Lys in the transition diet was 6.06 g/kg (P < 0.01). When urinary concentrations of urea were expressed relative to creatinine, the relative concentration of urea remained low until a dietary concentration of 6.08 g SID Lys/kg, above which the relative concentration of urea increased (P < 0.01). Stillbirth rate increased linearly with increasing SID Lys concentration in the transition diet (P < 0.001), thus the concentration of SID Lys should be kept as low as possible without impairing sow performance excessively. A carry-over effect on milk yield was observed, showing that a dietary SID Lys concentration of 5.79 g/kg during transition optimized milk production at an average yield of 13.5 kg/d (P = 0.04). Increasing loss of body fat in lactation was observed with increasing SID Lys concentration in the transition diet (P = 0.03). In conclusion, the transition diet of multiparous sows should contain 5.79 g SID Lys/kg when fed 3.8 kg/d (13.0 MJ ME/kg), for a total SID Lys intake of 22 g/d.

]]>
Research Fri, 01 Mar 2024 22:52:25 +0100 1cf44d50-10f0-4e02-b4b0-fc428612d08e
<![CDATA[Can individual variation in food neophobia explain variability in dairy calf feeding behavior patterns and performance?]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=7abbe23c-9327-406f-838f-ab8d6ccc96be&tx_pure_pure5%5BshowType%5D=pub&cHash=c3d77dc7d9d287891775fa44cf1b4975 Woodrum Setser, M. M., Neave, H. W., Costa, J. H.C. Food neophobia is the avoidance of novel feeds, arising from an attempt to avoid potentially toxic and unwanted feeds, and is very common in ruminants. In commercial dairy settings, hesitancy to consume novel feeds is detrimental to animal performance and may be associated with other traits that can negatively affect animals in intensive and modern production systems. The aim of this study was to investigate the relationship between food neophobia and the development of solid and milk feeding behaviors, and consequently with calf performance up to two weeks post-weaning. We subjected dairy calves at 83 ± 3 d of age to a food neophobia test with a novel feed (corn silage-based total mixed ration), a familiar feed (alfalfa hay), and an empty container. Behaviors measured from this food neophobia test were condensed into three factors using a principal component analysis: ‘Feed Avoidant’, ‘Active’, and ‘Attentive’. A regression analysis was performed to assess if scores for the three factors were associated with feeding behavior patterns measured via an automatic feeder system, including total milk intake, rewarded and unrewarded visits to the milk feeder, total calf starter intake, and age at which calves first consumed ≥ 1 kg of calf starter. Factor 1 (‘Feed Avoidant’) was positively associated with the number of rewarded visits to the automated milk feeder but was not associated with intake of calf starter or milk replacer, nor performance of dairy calves. The other factors identified from the food neophobia test showed associations with feeding behavior patterns and performance. Factor 2 (‘Active’) was positively associated with calf starter intake during the weaning, post-weaning, and total periods, and was associated with a younger age at which calves consumed 1 kg of calf starter. Factor 3 (‘Attentive’) was positively associated with number of rewarded visits to the feeder during preweaning, increased calf starter intake during weaning and total periods, and higher preweaning ADG. These results suggest that individual variation in the willingness to interact with novel and familiar feeds may not play a large role in the development of solid feeding behaviors or performance of group housed dairy calves, but other traits identified from the food neophobia test are associated with performance and feeding behavior that can be measured in standardized tests.

]]>
Research Wed, 01 May 2024 22:52:25 +0200 7abbe23c-9327-406f-838f-ab8d6ccc96be
<![CDATA[Redox balance and immunity of piglets pre‑ and post‑E. coli challenge after treatment with hemp or fish oil, and vitamin E]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=62274541-9cfe-44e2-9288-b68320ef0292&tx_pure_pure5%5BshowType%5D=pub&cHash=bf932f9055c6291507efd0146e8c25bb Madsen, P. A., Jensen, S. K., Lauridsen, C. Research Tue, 14 May 2024 22:52:26 +0200 62274541-9cfe-44e2-9288-b68320ef0292 <![CDATA[Climate and environmental effects of nutritional mitigation options to reduce enteric methane in dairy cattle]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=4d591def-463b-41c4-91b7-dc75255d0ecc&tx_pure_pure5%5BshowType%5D=pub&cHash=4e412133efd2b8e528438d36e361dd0d Dorca-Preda, T., Olijhoek, D. W., Mogensen, L., Lund, P., Kristensen, T. Nutritional mitigation strategies represent an option to reduce enteric methane emissions from ruminants, but these strategies must not have undesirable side effects. Therefore, the present study aimed to analyze the environmental effects of supplementation of typical dairy cow feeding rations in Denmark (S0) with 20 g extra fatty acids per kg dry-matter (S1), 10 g nitrate per kg dry-matter (S2), and 60 mg 3-nitrooxypropanol (3-NOP) per kg dry-matter (S3). A cradle-to-farm gate life cycle assessment approach was used, where fifteen environmental impacts were assessed to capture the environmental effects. Pairwise Monte Carlo simulations were conducted to identify statistically significant results. It was found that the climate impact per kg of milk decreased for all the strategies (−7 % in S1 and S2 and −13 % in S3) compared to S0. Furthermore, lower land use and land use change emissions were determined by the partial replacement of soybean meal with cracked rapeseed (in S1) or nitrate (in S2). The reduction in the level of enteric methane also contributed to decreases in the toxicity-related impacts of organic chemicals in S1. The use of nitrate in S2 also involved a decrease in the use of soybean meal, which contributed to decreases in the land use impacts. In strategies S2 and S3 increases in other environmental impacts were observed compared to S0 because of the manufacturing of nitrate or 3-NOP, or higher N excretion and emission at supplementation with nitrate. It was concluded that S3 was more effective in reducing the climate (and human-toxicity impacts of organic substances) impacts, while S1 caused small decreases in a wider range of environmental impacts. The present study has an important contribution to quantifying a wide range of environmental effects for intensive dairy and regarding the implementation of nutritional strategies in dairy cattle to reduce enteric methane.

]]>
Research Sat, 01 Jun 2024 22:52:26 +0200 4d591def-463b-41c4-91b7-dc75255d0ecc
<![CDATA[Generalized myasthenia gravis with acetylcholine receptor antibodies]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=b670de57-d904-428b-8ee2-bbb594eda7ca&tx_pure_pure5%5BshowType%5D=pub&cHash=8557a0515d01431bb92217ac0ca70077 Gilhus, N. E., Andersen, H., Andersen, L. K., et al. Background: Generalized myasthenia gravis (MG) with antibodies against the acetylcholine receptor is a chronic disease causing muscle weakness. Access to novel treatments warrants authoritative treatment recommendations. The Nordic countries have similar, comprehensive health systems, mandatory health registers, and extensive MG research. Methods: MG experts and patient representatives from the five Nordic countries formed a working group to prepare treatment guidance for MG based on a systematic literature search and consensus meetings. Results: Pyridostigmine represents the first-line symptomatic treatment, while ambenonium and beta adrenergic agonists are second-line options. Early thymectomy should be undertaken if a thymoma, and in non-thymoma patients up to the age of 50–65 years if not obtaining remission on symptomatic treatment. Most patients need immunosuppressive drug treatment. Combining corticosteroids at the lowest possible dose with azathioprine is recommended, rituximab being an alternative first-line option. Mycophenolate, methotrexate, and tacrolimus represent second-line immunosuppression. Plasma exchange and intravenous immunoglobulin are used for myasthenic crises and acute exacerbations. Novel complement inhibitors and FcRn blockers are effective and fast-acting treatments with promising safety profiles. Their use depends on local availability, refunding policies, and cost–benefit analyses. Adapted physical training is recommended. Planning of pregnancies with optimal treatment, information, and awareness of neonatal MG is necessary. Social support and adaptation of work and daily life activities are recommended. Conclusions: Successful treatment of MG rests on timely combination of different interventions. Due to spontaneous disease fluctuations, comorbidities, and changes in life conditions, regular long-term specialized follow-up is needed. Most patients do reasonably well but there is room for further improvement. Novel treatments are promising, though subject to restricted access due to costs.

]]>
Research Wed, 01 May 2024 22:52:26 +0200 b670de57-d904-428b-8ee2-bbb594eda7ca
<![CDATA[Individuality of calves]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=72f5bb54-4d83-4e23-a782-d5517970ba49&tx_pure_pure5%5BshowType%5D=pub&cHash=bb1af3167d9b5cc5431c36494b53e4ff Woodrum Setser, M. M., Neave, H. W., Costa, J. H.C. Animal personality has established connections with animal performance, resilience, and welfare which are related to stable behavioral patterns. Precision livestock technologies introduce the opportunity to measure these behavior patterns automatically and noninvasively. Thus, the primary aim of this study was to determine if personality traits in dairy calves measured via standardized personality assessments were associated with activity measured via a commercially available accelerometer. Secondary aims of this study were to investigate if personality traits were associated with feeding behaviors measured via an automatic feeding system (AFS) and with average daily gain (ADG). We characterized personality traits of Holstein calves (n = 49) utilizing standardized personality (novel environment, novel person, novel object, and startle) tests. Behaviors from these tests were summarized and 3 factors were extracted from a principal component analysis to represent calf personality traits: fearful, active, and explorative. Factor scores were regressed against behaviors from the accelerometer and AFS and with ADG. We found that calves that were more active were associated with taking more steps in the home environment, consuming more calf starter, and with reaching the benchmark of 1 kg of starter consumed in a day at a younger age. The trait active was also associated with greater ADG throughout the study. In addition, calves that were more explorative in the personality tests were associated with less starter consumed and lower ADG specifically during the weaning period. The findings of this research contribute to the existing literature by further establishing the links between personality traits and the daily behavioral patterns and performance of young calves. This study suggests the potential for using precision technology to assess and characterize personality traits, thereby enhancing their practical applicability on farms. Future research should focus on evaluating how personality traits, as measured through standardized assessments and precision technologies, correlate with deviations in behavior observed in dairy calves during stressors.

]]>
Research Wed, 01 May 2024 22:52:26 +0200 72f5bb54-4d83-4e23-a782-d5517970ba49
<![CDATA[Strengthening Animal Welfare in the Green Transition]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=e15c030c-e6f9-4f48-a39a-2c73d0cb92ee&tx_pure_pure5%5BshowType%5D=pub&cHash=348d6d51555e92cbb904b0a33215e38a Mc Loughlin, E. T. Research Tue, 19 Mar 2024 22:52:26 +0100 e15c030c-e6f9-4f48-a39a-2c73d0cb92ee <![CDATA[Book Review: Indifference: On the Praxis of Interspecies Being]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=3738a9f1-9afd-4c16-a808-147ad56dc145&tx_pure_pure5%5BshowType%5D=pub&cHash=71fa01321fe44145ce2555fef79a37bd Mc Loughlin, E. T. Research Sun, 28 Apr 2024 22:52:26 +0200 3738a9f1-9afd-4c16-a808-147ad56dc145 <![CDATA[Effects of heat stress on feed intake, milk yield, milk composition, and feed efficiency in dairy cows: A meta-analysis]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=3869f283-bbcb-47fd-8ebe-5eae75863e4c&tx_pure_pure5%5BshowType%5D=pub&cHash=5aa595350a11dd7af8073370e9bd1ef6 Chen, L., Thorup, V. M., Kudahl, A. B., Østergaard, S. Heat stress compromises dairy production by decreasing feed intake and milk yield, and it may also alter milk composition and feed efficiency. However, little information is available for evaluating such effects across different levels of heat stress and cows enrolled in heat stress studies. The objectives of this study were to evaluate the effects of heat stress on dry matter intake (DMI), energy-corrected milk (ECM), milk composition, and feed efficiency (kg ECM/kg DMI) and to investigate the relationship between such effects and heat stress intervention and animal characteristics by using meta-analytical approaches. Data from 31 studies (34 trials) fulfilled the inclusion criteria and were used for analysis. Results showed that heat stress decreased DMI, ECM, and milk protein concentration, but did not alter milk fat concentration or feed efficiency. Meta-regression confirmed that such reductions in DMI and ECM were significantly associated with increasing temperature-humidity index (THI). Over the period of heat stress, for each unit increase in THI, DMI and ECM decreased by 4.13% and 3.25%, respectively, in mid-lactation cows. Regression models further revealed the existence of a strong interaction between THI and lactation stage, which partially explained the large heterogeneity in effect sizes of DMI and ECM. The results indicated a need for more research on the relationship between the effect of heat stress and animal characteristics. This study calls for the implementation of mitigation strategies in heat-stressed herds due to the substantial decrease in productivity.

]]>
Research Sun, 19 Nov 2023 22:52:26 +0100 3869f283-bbcb-47fd-8ebe-5eae75863e4c
<![CDATA[In vivo assessment of the antiparasitic effects of Allium sativum L. and Artemisia absinthium L. against gastrointestinal parasites in swine from low-input farms]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=fe9f51f5-84f6-4374-b9e9-725be24b57cd&tx_pure_pure5%5BshowType%5D=pub&cHash=49bf4df3aebce6ba6f0c6ebb74164398 Băieş, M. H., Cotuţiu, V. D., Spînu, M., et al. Background: Ethno-veterinary practices could be used as a sustainable developmental tool by integrating traditional phytotherapy and husbandry. Phytotherapeutics are available and used worldwide. However, evidence of their antiparasitic efficacy is currently very limited. Parasitic diseases have a considerable effect on pig production, causing economic losses due to high morbidity and mortality. In this respect, especially smallholders and organic producers face severe challenges. Parasites, as disease causing agents, often outcompete other pathogens in such extensive production systems. A total of 720 faecal samples were collected in two farms from three age categories, i.e. weaners, fatteners, and sows. Flotation (Willis and McMaster method), modified Ziehl–Neelsen stained faecal smear, centrifugal sedimentation, modified Blagg technique, and faecal cultures were used to identify parasites and quantify the parasitic load. Results: The examination confirmed the presence of infections with Eimeria spp., Cryptosporidium spp., Balantioides coli (syn. Balantidium coli), Ascaris suum, Oesophagostomum spp., Strongyloides ransomi, and Trichuris suis, distributed based on age category. A dose of 180 mg/kg bw/day of Allium sativum L. and 90 mg/kg bw/day of Artemisia absinthium L. powders, administered for 10 consecutive days, revealed a strong, taxonomy-based antiprotozoal and anthelmintic activity. Conclusions: The results highlighted the therapeutic potential of both A. sativum and A. absinthium against gastrointestinal parasites in pigs. Their therapeutic effectiveness may be attributed to the content in polyphenols, tocopherols, flavonoids, sterols, sesquiterpene lactones, and sulfoxide. Further research is required to establish the minimal effective dose of both plants against digestive parasites in pigs.

]]>
Research Mon, 01 Apr 2024 22:52:26 +0200 fe9f51f5-84f6-4374-b9e9-725be24b57cd
<![CDATA[Lige børn leger bedst]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=4a926891-1fc5-422f-8f7b-a274751a8943&tx_pure_pure5%5BshowType%5D=pub&cHash=f0b156295705b0cf7ef405db16bb6946 Thomsen, P. T. Communication Mon, 01 Apr 2024 22:52:26 +0200 4a926891-1fc5-422f-8f7b-a274751a8943 <![CDATA[Quantitative distribution of flavan-3-ols, procyanidins, flavonols, flavanone and salicylic acid in five varieties of organic winter dormant Salix spp. by LC-MS/MS]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=d1ae1019-1d9a-4e58-800d-c6cb96754f4a&tx_pure_pure5%5BshowType%5D=pub&cHash=1991c3be570a0029b189186e8a2ed173 Curtasu, M. V., Nørskov, N. P. Willow trees (Salix spp.) exhibit remarkable genetic and phenotypic diversity, yielding a broad spectrum of bioactive compounds, notably valuable phenolic compounds such as condensed tannins (phenolic polymers), flavonoids, salicylic glucosides, and phenolic compounds. These enhance the economic value of willow crops and make them suitable for circular bioeconomy. Phenolic compounds known for their diverse applications as antioxidants, antimicrobial agents, pharmaceuticals, nutraceuticals and antiseptics and more, find a natural source in willow. This study aimed to elucidate the composition of 12 flavonoids and salicylic acid in different segments of five organic winter dormant willow species (S. daphnoides, S. fragilis, S. dasyclados, S. viminalis, and S. dasyclados x viminalis) using quantitative analysis and providing valuable insights into their high-value phenolic compounds. Separation into buds, wood and bark segments allowed for a precise characterization of the location of certain phenolic compounds and quantification using LC-MS/MS techniques. LC-MS/MS is an analytical technique known for its increased sensitivity and chromatographic precision. Among the findings, catechin emerged as the predominant flavan-3-ol in all Salix species, with the highest concentration in the buds of Salix viminalis (7.26 mg/g DM). Naringenin exhibited species-specific variations, with S. dasyclados and S. viminalis recording the highest levels. Salicylic acid concentrations peaked in S. dasyclados (5.38 mg/g DM) and S. daphnoides (4.43 mg/g DM), particularly within the bark. When evaluating other individual flavonoids and total polyphenol content (TPC), disparities between buds, bark, and wood became evident, with wood consistently displaying the lowest content. Notably, the higher concentration of polyphenolic compounds in willow bark can be attributed to its susceptibility to external threats and its role as a robust defense mechanism against pathogens and herbivores. This study underscores the significance of diverse willow species as a source of high-value phenolic compounds, distributed differentially across plant parts and species. This knowledge holds promise for their potential applications in the circular bioeconomy.

]]>
Research Thu, 01 Feb 2024 22:52:26 +0100 d1ae1019-1d9a-4e58-800d-c6cb96754f4a
<![CDATA[Oplistning af forskningsspørgsmål og -emner relevant for klimatilpasning af landbruget]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=4e3af7fa-cf32-4a9a-9701-87eaf936a587&tx_pure_pure5%5BshowType%5D=pub&cHash=64ad2c417ad8888113899d09a0394f86 Olesen, J. E., Andersen, M. N., Greve, M. H., et al. Commissioned Thu, 25 Apr 2024 22:52:26 +0200 4e3af7fa-cf32-4a9a-9701-87eaf936a587 <![CDATA[Metode til huldtilpasning af mink]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=02318065-2045-4f26-9381-8e39780169aa&tx_pure_pure5%5BshowType%5D=pub&cHash=9390c3ac7770e61b3dafb98769a5a949 Møller, S. H. Commissioned Fri, 12 Apr 2024 22:52:26 +0200 02318065-2045-4f26-9381-8e39780169aa <![CDATA[Animal health, welfare and production problems in organic weaner pigs]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=2cd0c046-df5d-4af5-b846-79bcf05810cc&tx_pure_pure5%5BshowType%5D=pub&cHash=73198a1e0cae3b31d6f1f24af4efdce7 Leeb, C., Hegelund, L., Edwards, S., et al. This paper reviews the available information on the different health and animal welfare issues in organic pigs in relation to weaning. It addresses the most relevant health and welfare problems and reviews their potential hazards and associated risk factors. Regarding health, problems related to post weaning diarrhoea, cold stress, skin lesions, endoparasites and post weaning multisystemic wasting syndrome are described. Reasons for distress and frustration in weaned piglets are identified as mainly separation from the mother, a new environment, mixing and fear of humans. Finally, hazards and risk factors for health and welfare in organic weaners are related to animal characteristics, housing systems, feed/nutrition and management. Generally, it is concluded that diseases around weaning are multifactorial in nature, with several factors contributing simultaneously as stressors at the time of weaning. In order to solve problems around weaning, the complexity and the individuality of farm systems need to be taken into account.

]]>
Research Wed, 01 Oct 2014 22:52:26 +0200 2cd0c046-df5d-4af5-b846-79bcf05810cc
<![CDATA[Description of organic pig production in Europe]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=6ed34998-7c71-4169-ba35-7d72822689be&tx_pure_pure5%5BshowType%5D=pub&cHash=2f88aa09bb9cdfe6312a8d4a03383bd9 Früh, B., Bochicchio, D., Edwards, S., et al. With the aim to identify health and welfare strategies in organic pig production, a description of the different organic production systems was realized in eight European countries (Austria, Denmark, France, Germany, Italy, Sweden, Switzerland and UK). This description was based on the following features: numbers of organic farms and organic pigs, market shares, housing and management characteristics, feeding characteristics, main health problems and relevant differences to the EU regulation existing at the time of the project. The results were primarily based on statistics, country-specific regulations as well as on expert and stakeholder interviews. Organic farming and organic pig production are rapidly developing in European countries. The European country with the highest number of organic pigs is Germany. Organic pig production represents aminor part of the whole pig production in all surveyed countries. All features that were analysed varied greatly between countries with the most striking one being the housing of pigs that can be completely outdoors on pasture for most UK farms and always indoors with an access to an outdoor run, during part of their life, for most farms of German speaking countries.

]]>
Research Wed, 01 Oct 2014 22:52:26 +0200 6ed34998-7c71-4169-ba35-7d72822689be
<![CDATA[Radial versus femoral access in patients with acute coronary syndrome undergoing invasive management]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=87b6deb9-989d-4b28-8193-f6410e81497a&tx_pure_pure5%5BshowType%5D=pub&cHash=108aac8513e1b9910ed287746718ab5a Völz, S., Angerås, O., Koul, S., et al. Aims: In the Bivalirudin versus Heparin in ST-Segment and Non-ST-Segment Elevation Myocardial Infarction in Patients on Modern Antiplatelet Therapy in the Swedish Web System for Enhancement and Development of Evidence-based Care in Heart Disease Evaluated according to Recommended Therapies Registry Trial (VALIDATE-SWEDEHEART), bivalirudin was not superior to unfractionated heparin in patients with acute coronary syndrome undergoing invasive management. We assessed whether the access site had an impact on the primary endpoint of death, myocardial infarction or major bleeding at 180 days and whether it interacted with bivalirudin/unfractionated heparin. Methods and results: A total of 6006 patients with acute coronary syndrome planned for percutaneous coronary intervention were randomised to either bivalirudin or unfractionated heparin. Arterial access was left to the operator discretion. Overall, 90.5% of patients underwent transradial access and 9.5% transfemoral access. Baseline risk was higher in transfemoral access. The unadjusted hazard ratio for the primary outcome was lower with transradial access (hazard ratio 0.53, 95% confidence interval 0.43–0.67, p<0.001) and remained lower after multivariable adjustment (hazard ratio 0.56, 95% confidence interval 0.52–0.84, p<0.001). Transradial access was associated with lower risk of death (hazard ratio 0.41, 95% confidence interval 0.28–0.60, p<0.001) and major bleeding (hazard ratio 0.57, 95% confidence interval 0.44–0.75, p<0.001). There was no interaction between treatment with bivalirudin and access site for the primary endpoint (p=0.976) or major bleeding (p=0.801). Conclusions: Transradial access was associated with lower risk of death, myocardial infarction or major bleeding at 180 days. Bivalirudin was not associated with less bleeding, irrespective of access site.

]]>
Research Sun, 01 Sep 2019 22:52:26 +0200 87b6deb9-989d-4b28-8193-f6410e81497a
<![CDATA[Undersøgelse af behov for kupering af lammehaler]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=8c06e5a6-24c8-4f0b-97f7-fc3e1f214516&tx_pure_pure5%5BshowType%5D=pub&cHash=c06aa8506c47ab2e07b548c43c02d069 Henriksen, B. I. F. Commissioned Mon, 08 Apr 2024 22:52:26 +0200 8c06e5a6-24c8-4f0b-97f7-fc3e1f214516 <![CDATA[Obduktioner giver ny viden]]> https://anivet.au.dk/en/current-news/publications?tx_pure_pure5%5Baction%5D=single&tx_pure_pure5%5Bcontroller%5D=Publications&tx_pure_pure5%5Bid%5D=c092668e-a7fb-4667-a5e3-0239a33434ec&tx_pure_pure5%5BshowType%5D=pub&cHash=2d97c8e7ecdb1412bb53079c705771dc Thomsen, P. T. Communication Mon, 01 Apr 2024 22:52:26 +0200 c092668e-a7fb-4667-a5e3-0239a33434ec