Assisted reproductive technologies (ART) in cattle breeding encompass both in vivo and in vitro techniques, each offering unique approaches to enhance reproductive efficiency, genetic advancement, and overall herd productivity. We have datasets from two large research projects on transcriptome sequencing (RNAseq) of calves obtained from in vivo and in vitro techniques.
This masters project will be about calling Single Nucleotide Polymorphisms (SNPs) and Copy Number Variations (CNVs) from gene expression (RNASeq) datasets across different internal organs of calves (hypothalamus, testicle, liver, pituitary, muscle, and adrenal). They are abbreviated as eQTLs and eCNVs, respectively.
The work will then move towards relating eQTLs and eCNVs to a list of differentially expressed genes (DEGs) and differentially methylated regions (DMRs) that are provided.
Anytime
Dept. of Animal & Veterinary Sciences, AU Viborg
(Remote or Hybrid Work is Possible)
30 ECTS: Theoretical thesis based on literature studies and/or analysis of issued and edited data sets.
